As we've discussed before, nothing runs better than a single 4 barrel on an engine (well, maybe fuel injection, but that is a different story altogether). BUT, nothing looks cooler than a few carbs sitting on top of an engine.
When I changed from the single 4 barrel on my 23 to the 2 x 2 Vintage Speed setup I did lose some smoothness, but I sure liked the looks a whole lot more. My 27 has only had a 2 x 4 setup for the 20+ years of it's existance, and that will always be there.
So, my vote goes for the 3 x 2 setup for your car. Crossrams are really not all that bad on the street, I have seen a few and the owners say they perform well, but I think the 3 x 2 would be a little easier to tune and maintain.
Don